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Image Search Results
Journal: Cancers
Article Title: Systematic Roadmap for Cancer Drug Screening Using Zebrafish Embryo Xenograft Cancer Models: Melanoma Cell Line as a Case Study
doi: 10.3390/cancers13153705
Figure Lengend Snippet: Impact of site of cell implantation on tumor area ascertained by imaging. ( a ) Comparison of the tumor areas of engrafted embryos at three time points grouped by the sites of injection. ( b ) Comparison of the tumor areas of engrafted embryos microinjected into different injection sites grouped by time points. Data are presented as box-leaf plots, where the box indicates IQR, line the median value and leafs the 5–95 percentile range. ( c ) Change in tumor area tracked for individual embryos implanted into the PCS and dorsal PVS. Only zebrafish possessing a tumor area higher than a pre-defined threshold were considered for the analysis . Each dot represents an individual embryo. The experiment was designed as a balanced incomplete block assay. Mixed factorial ANOVA was performed with the anovalator STATA command (*** = p -value < 0.001; **** = p -value < 0.0001).
Article Snippet: Thus, a mixed factorial ANOVA was employed and then used to compare groups with the
Techniques: Imaging, Comparison, Injection, Blocking Assay